Abstract: Based on the vehicle trajectory influenced by driving habits and experience, visual field and traffic environment, vehicle dynamic response is studied under typical driving trajectories, e.g.normal, desired, cutting, drifter, swing and correcting trajectories. Road curved sections with the road axis defined by the six vehicle trajectories are designed in Carsim environment, and the left front wheel of the vehicle is assumed to move along the road axis. During simulation, vehicle dynamic parameters are monitored and recorded. The results show that while vehicle travels along the cutting and normal trajectories, vehicle could pass through the curved section in safety, efficient and comfortable status; while vehicle travels along correcting and swing trajectories, driving stability and driving comfort are worse.