Abstract: 2D nano-materials have attracted extensive attention in the development and application of membrane materials due to their excellent physical and chemical properties and easy regulation. 2D membranes can be prepared by layer-by-layer stacking of 2D materials. However, how to modify the structure and properties of nano-sheets is a frontier research issue in this field. In this study, a high performance composite membrane based on MXene（Ti₃C₂T_x）/MoS₂ was prepared by a mild and rapid pre-oxidation method. The test results show that the water permeability of the composite membrane can be improved greatly. The rejection rate of the targeted dye can reach as high as 99.9%. Compared with the un-oxidized MXene membrane, the improved composite membrane can make the osmotic inhibition efficiency to NaCl and MgCl₂ increased by 48.4% and 82.0% separately. In addition, the composite membrane can also show long term stability in water in terms of both structure/appearance and flux, providing actually a new strategy and idea of MXene（Ti₃C₂T_x）for MXene membrane structure regulation and performance optimization.