Abstract: In this paper, a wearable low-intensity focused ultrasound therapy device was designed to treat human soft tissue injury, relieve pain, and speed up the condition. Firstly, a QI standard wireless charging module was used to provide energy for the entire device. And an integrated conversion circuit with high conversion rate was designed to convert the voltage from 3.3 V to 5 V, providing voltage for the driving circuit. Then the remote control device controlled by the nRF24L01 module was used to control the ultrasonic rehabilitation paste. The STM32L151 microcontroller combined with PID algorithm can produce 1 MHz PWM wave, and the control drive circuit can drive piezoelectric ceramic chip to produce frequency of 1 MHz, strength of 100 mW/cm², 132 mW/cm², 150 mW/cm² three gears ultrasonic. The device possesses the characteristics, including small size, fast charging, light weight, low cost, no coupling agent, wearable, high electro-acoustic conversion efficiency.